Globally, gay men and other men who have sex with men are 19 times more likely to be living with HIV than the general population. The incidence of HIV among gay men and other men who have sex with men is rising in several parts of the world. Structural factors, such as stigma, discrimination and violence based on sexual orientation and gender identity and the criminalization of same-sex sexual practices, contribute to hindering the availability, access and uptake of HIV prevention, testing and treatment services among gay men and other men who have sex with men.