Annual numbers of new HIV infections in western and central Africa declined by 46% between 2010 and 2023. The high numbers of new infections among people from key populations and adolescent girls and young women are challenges, however, and call for increased investment in primary prevention programmes. In 2023, adolescent girls and young women aged 15–24 years accounted for 19% of all new HIV infections. The expansion of differentiated services for HIV treatment have yielded marked progress, with 81% [62–97%] of people living with HIV knowing their status, 76% [59–92%] receiving antiretroviral therapy, and 70% [61–81%] having a suppressed viral load. The number of adults aged 15 years and over receiving HIV treatment has more than doubled since 2015. Between 2010 and 2023, numbers of AIDS-related deaths decreased by 55%. Related links: New UNAIDS report shows AIDS pandemic can be ended by 2030, but only if leaders boost resources and protect human rights now | Full report