My friends, we must continue to collectively reflect on how we can become more fit for purpose for the post-2015 transformative agenda—both at UNAIDS and in the United Nations system as a whole. We discussed this at the Chief Executives Board and agreed that a United Nations system that can deliver on the post-2015 agenda must effectively meet the challenges of the twenty-first century. These challenges are diverse and complex and demand the effective coordination of government, civil society, the private sector, academia and others. UNAIDS is uniquely placed to bring together all actors.